: either of two physiologically active isomers C21H30O2 from hemp plant resin
especially : one that is the chief intoxicant in marijuana
When a person tokes, eats or vapes cannabis, a wave of THC, or tetrahydrocannabinol, washes into the brain. Laura Sanders
THC, the main chemical component of marijuana, has been shown to reduce nausea and increase appetite in chemotherapy patients. Andrew Weil
THC disappears from blood quickly as it is absorbed in the brain, making blood tests a more reliable measure of recent use but not a great correlate of impairment. Eliza Gray

Examples of THC in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Fast-Acting Gummies Conventional cannabis edibles are notorious for often taking more than an hour or longer for the user to feel the psychoactive effects of THC. A.j. Herrington, Forbes.com, 27 May 2025 However, hemp, which is a type of cannabis plant with a lower content of THC, was legalized in the state in 2019. Mandy Taheri, MSNBC Newsweek, 23 May 2025 Texas lawmakers have passed a ban on nonmedical sales of THC, the intoxicating ingredient in cannabis, sending the measure to Gov. Greg Abbott (R). Saul Elbein, The Hill, 22 May 2025 According to a 2018 study published in Frontiers in Pharmacology, cannabis, especially strains rich in CBD and low to moderate in THC, can help reduce anxiety, encourage focus, and foster open-minded thinking—ideal for tarot sessions where clarity and presence are key. Matt Rozo, Mercury News, 20 May 2025 See All Example Sentences for THC

Word History

Etymology

tetrahydrocannabinol

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of THC was in 1967

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Cite this Entry

“THC.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/THC. Accessed 31 May. 2025.

Medical Definition

: either of two physiologically active isomers C21H30O2 that occur naturally in hemp plant resin or are synthetically prepared:
a
: one that is the chief intoxicant in marijuana and is used medicinally

called also delta-9-tetrahydrocannabinol, delta-9-THC

see dronabinol
b
: one that is present in marijuana only in minute quantities

More from Merriam-Webster on THC

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