antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Countries like Ukraine wanted to be in NATO not to antagonize Russia, but to shield themselves from it. Josh Hammer, MSNBC Newsweek, 1 Apr. 2025 These notions of nonconformity antagonized directly by various religious leaders, while the Civil War (1642–51) irreparably shook the British monolith. Tessa Solomon, ARTnews.com, 28 Mar. 2025 Beyond the economic threats, Trump has repeatedly antagonized and belittled historic partners, notably the one with which the U.S. shares a 5,500-mile (8,900-kilometer) border. Time, 28 Mar. 2025 Other fans have been openly antagonizing the hockey gods with ideas for the most Team Chaos-worthy way the record could fall. Sean McIndoe, New York Times, 26 Mar. 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 9 Apr. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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