1
: a soiling or disfiguring mark : spot
2
: a mark of reproach : moral flaw
3
: a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (such as a complementary nucleic acid or a radiolabeled antibody) compare southern blot, western blot
blotted; blotting
1
: to spot, stain, or spatter with a discoloring substance
2
3
a
: to dry (something, such as writing) with an absorbing agent
hastily blotted her letter
b
: to remove with absorbing material
blotting up spilled water
1
: a lone backgammon man exposed to capture
2
archaic
: a weak or exposed point
Synonyms
Examples of blot in a Sentence
Noun (1)
the bribery scandal was a blot on his reputation
Verb
Don't rub the wine stain. Blot it dry with a paper towel.
Blot your lipstick with a tissue.
Recent Examples on the Web
Mary Cornetta, Better Homes & Gardens, 29 Oct. 2024
Not a single blot of paint in the Tate Modern repels the female soul, though the £84 annual membership fee may dissuade some female wallets.
—Andrea Long Chu, Vulture, 28 June 2024
Iman Balagam, Vogue, 29 Oct. 2024
Let the water soak into the upholstery fibers for about three minutes and then blot the area again.
—Mary Marlowe Leverette, Southern Living, 28 Oct. 2024
See all Example Sentences for blot 
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Noun
First, blot as much of the area as possible when something spills to remove excess moisture.
—Mary Cornetta, Better Homes & Gardens, 29 Oct. 2024
Not a single blot of paint in the Tate Modern repels the female soul, though the £84 annual membership fee may dissuade some female wallets.
—Andrea Long Chu, Vulture, 28 June 2024
Verb
Harris, on the other hand, recommends the blotting method: apply a layer of matte lip crayon, gently blot with tissue, and then apply a second layer for the most powerful pigment.
—Iman Balagam, Vogue, 29 Oct. 2024
Let the water soak into the upholstery fibers for about three minutes and then blot the area again.
—Mary Marlowe Leverette, Southern Living, 28 Oct. 2024
See all Example Sentences for blot
Dictionary Entries Near blot
Cite this Entry
“Blot.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/blot. Accessed 26 Nov. 2024.
Copy CitationKids Definition
blot
1 of 2 nounblot
2 of 2 verb
blotted; blotting
2
3
4
: to dry with something absorbent
5
: to mark or become marked with a blot
Medical Definition
blot
noun
: a nitrocellulose sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and that is used to identify specific components of the spots by applying a suitable molecular probe (as a complementary nucleic acid or a radiolabeled antibody) see northern blot, southern blot, western blot
blot
transitive verb
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