clozapine
noun
clo·za·pine
ˈklō-zə-ˌpēn 
: an antipsychotic drug C18H19ClN4 used in the treatment of schizophrenia
Examples of clozapine in a Sentence
Recent Examples on the Web
The benefits of clozapine outweigh the risks of neutropenia, a rare but potentially life-threatening side effect, doctors say.
—
Emily Kay Votruba, EverydayHealth.com, 3 Mar. 2025
At least one, Ryan Dunleavy of Brentwood, Tennessee, died from a deadly cocktail of fentanyl, MDMA (ecstasy) and clozapine.
—Kirsten Fiscus, The Tennessean, 14 June 2024
Medication side effects: Nonsteroidal anti-inflammatory drugs (NSAIDs) like Motrin (ibuprofen), serotonin receptor agonists like Clozaril (clozapine), and anticancer medications can all affect GI health.
—Mark Gurarie, Health, 2 Nov. 2024
Currently, the drug clozapine is the only option for treatment-resistant schizophrenia.
—Claire Bugos, Verywell Health, 30 Sep. 2024
The center is also participating in the clozapine study.
—Angela Roberts, Baltimore Sun, 1 July 2024
Other countries have been more discerning about clozapine’s public health calculus, resulting in less-stringent monitoring regulations and more widespread clozapine prescribing.
—Brian Barnett, STAT, 9 May 2022
To prevent and rapidly address cases of agranulocytosis, the FDA requires clozapine’s manufacturers to jointly administer the clozapine REMS program.
—Brian Barnett, STAT, 9 May 2022
Frustratingly, the antipsychotic that works best against schizophrenia’s symptoms—clozapine, which emerged in the late 1980s—can have the nastiest unwanted effects, including weight gain, diabetes, and excessive sleepiness.
—WIRED, 10 Feb. 2023
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Emily Kay Votruba, EverydayHealth.com, 3 Mar. 2025
At least one, Ryan Dunleavy of Brentwood, Tennessee, died from a deadly cocktail of fentanyl, MDMA (ecstasy) and clozapine.
—Kirsten Fiscus, The Tennessean, 14 June 2024
Medication side effects: Nonsteroidal anti-inflammatory drugs (NSAIDs) like Motrin (ibuprofen), serotonin receptor agonists like Clozaril (clozapine), and anticancer medications can all affect GI health.
—Mark Gurarie, Health, 2 Nov. 2024
Currently, the drug clozapine is the only option for treatment-resistant schizophrenia.
—Claire Bugos, Verywell Health, 30 Sep. 2024
The center is also participating in the clozapine study.
—Angela Roberts, Baltimore Sun, 1 July 2024
Other countries have been more discerning about clozapine’s public health calculus, resulting in less-stringent monitoring regulations and more widespread clozapine prescribing.
—Brian Barnett, STAT, 9 May 2022
To prevent and rapidly address cases of agranulocytosis, the FDA requires clozapine’s manufacturers to jointly administer the clozapine REMS program.
—Brian Barnett, STAT, 9 May 2022
Frustratingly, the antipsychotic that works best against schizophrenia’s symptoms—clozapine, which emerged in the late 1980s—can have the nastiest unwanted effects, including weight gain, diabetes, and excessive sleepiness.
—WIRED, 10 Feb. 2023
Cite this Entry
“Clozapine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clozapine. Accessed 16 Mar. 2025.
Copy CitationMedical Definition
clozapine
noun
clo·za·pine
ˈklō-zə-ˌpēn
: an antipsychotic drug C18H19ClN4 with serious side effects (as seizures and agranulocytosis) that is used in the management of schizophrenia
Note: Clozapine is marketed under the trademark Clozaril.
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