cross-resistance

noun

cross-re·​sis·​tance ˌkrȯs-ri-ˈzi-stən(t)s How to pronounce cross-resistance (audio)
: tolerance (as of a bacterium) to a usually toxic substance (such as an antibiotic) that is acquired not as a result of direct exposure but by exposure to a related substance

Word History

First Known Use

1946, in the meaning defined above

Time Traveler
The first known use of cross-resistance was in 1946

Dictionary Entries Near cross-resistance

Cite this Entry

“Cross-resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cross-resistance. Accessed 23 Nov. 2024.

Medical Definition

cross-resistance

noun
cross-re·​sis·​tance ˌkrȯs-ri-ˈzis-tən(t)s How to pronounce cross-resistance (audio)
: tolerance (as of a bacteria, malignant cell, or insect) to a usually toxic substance (as an antibiotic, chemotherapy drug, or pesticide) that is acquired not as a result of direct exposure but by exposure to a related substance
The history of drug resistance in falciparum malaria suggests that these compounds may also enjoy only a short-lived glory and that cross-resistance with related compounds can be expected.David J. Wyler, The Journal of the American Medical Association
… paclitaxel and docetaxel are being incorporated into adjuvant regimens on the basis of their antitumor activity in advanced breast cancer and the absence of cross-resistance with doxorubicin.Charles L. Shapiro, et al., The New England Journal of Medicine
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