epigenetic

adjective

epi·​ge·​net·​ic ˌe-pə-jə-ˈne-tik How to pronounce epigenetic (audio)
1
a
: of, relating to, or produced by the chain of developmental processes in epigenesis that lead from genotype to phenotype after the initial action of the genes
b
: relating to, being, or involving changes in gene function that do not involve changes in DNA sequence
epigenetic inheritance
2
of a deposit or structure : formed after the laying down of the enclosing rock
epigenetically adverb

Examples of epigenetic in a Sentence

Recent Examples on the Web
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Over evolutionary time the supergene is likely to accumulate even more gene variants and epigenetic tags that complement an aggressive phenotype, in keeping with the theory behind the evolution of chromosomes associated with sexes. Donna L. Maney, Scientific American, 18 Feb. 2025 Another critical transition also occurs at a specific point in time in the process by which normal cells are transformed into cancer cells, as the result of an accumulation of both genetic and epigenetic changes. Thomas G. Moukawsher, Newsweek, 6 Feb. 2025 Focusing on epigenetic reversal could be akin to treating a symptom and not a cause, the study concludes. New Atlas, 2 Feb. 2025 That past abundance may have locked into place structural and epigenetic changes in the trees that are mismatched to today’s drier world. Alana Chin, The Conversation, 9 Jan. 2025 See All Example Sentences for epigenetic

Word History

Etymology

epi- + genetic, after epigenesis

First Known Use

1883, in the meaning defined at sense 1a

Time Traveler
The first known use of epigenetic was in 1883

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Cite this Entry

“Epigenetic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/epigenetic. Accessed 1 Mar. 2025.

Medical Definition

epigenetic

adjective
epi·​ge·​net·​ic -jə-ˈnet-ik How to pronounce epigenetic (audio)
1
: of, relating to, or produced by epigenesis
the epigenetic nature of vertebrate development
2
: relating to, being, or involving a modification in gene expression that is independent of the DNA sequence of a gene
epigenetic carcinogenesis
epigenetic inheritance
Methylation is one of many epigenetic signals—chemical changes to DNA and its associated proteins—that modify gene activity without altering the genetic information itself.Tina Hesman Saey, Science News
epigenetically adverb
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