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insulin resistance
noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes
Examples of insulin resistance in a Sentence
Recent Examples on the Web
Blood Sugar Imbalance: Juices can be high in naturally occurring sugars, which may impact individuals with diabetes or insulin resistance.
—Dominique Fluker, Essence, 10 Jan. 2025
Polyphenols may support carbohydrate (glucose) metabolism and reduce insulin resistance, a primary characteristic of type 2 diabetes.
—Amy Brownstein, Ms, Rdn, Verywell Health, 20 Dec. 2024
Aspartame could raise insulin resistance by affecting a brain receptor linked to insulin sensitivity.
—Isabel Vasquez Rd Ldn, Health, 3 Dec. 2024
This research suggests that an 8 to 10 percent decrease in BMI may help with insulin resistance—that’s why semaglutide’s 16 percent BMI reduction is so appealing, Bensignor says.
—Lauren J. Young, Scientific American, 25 Oct. 2024
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Word History
First Known Use
1927, in the meaning defined above
Time Traveler
The first known use of insulin resistance was
in 1927
Dictionary Entries Near insulin resistance
Cite this Entry
“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 18 Jan. 2025.
Medical Definition
insulin resistance
noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
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