interstitial

adjective

in·​ter·​sti·​tial ˌin-tər-ˈsti-shəl How to pronounce interstitial (audio)
1
: occurring in or being an interval or intervening space or segment : of, relating to, or forming an interstice
an interstitial space
… the site has been running interstitial ads, which consist of a full page of advertising between editorial pages, for a little more than a year.Carl Sullivan
2
a
: situated within but not restricted to or characteristic of a particular organ or tissue
used especially of fibrous tissue
b
: affecting the interstitial tissues of an organ or part
interstitial cystitis
3
: being or relating to a crystalline compound in which usually small atoms or ions of a nonmetal occupy holes between the larger metal atoms or ions in the crystal lattice
interstitially adverb

Examples of interstitial in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
It’s set in the present but several interstitial chapters flash back to the ‘80s and ’90s, when the women were getting their start as ruthless-but-funny contract killers. Chris Hewitt, Boston Herald, 23 Mar. 2025 Plenty of other conditions like pelvic floor dysfunction, interstitial cystitis (a.k.a. painful bladder syndrome), and yeast infections can be easy to confuse with UTIs. Korin Miller, SELF, 17 Mar. 2025 However, subsequent updates removed legitimate functionality, replacing it with tactics to maximize ad revenue through full-screen interstitial video ads. Zak Doffman, Forbes, 5 Mar. 2025 She was tested for Celiac disease and Crohn's disease before landing on the interstitial cystitis diagnosis, and even developed an eating disorder and experienced hair loss during that time. Jessica Wang, EW.com, 23 Jan. 2025 See All Example Sentences for interstitial

Word History

First Known Use

1646, in the meaning defined at sense 1

Time Traveler
The first known use of interstitial was in 1646

Browse Nearby Words

Cite this Entry

“Interstitial.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/interstitial. Accessed 30 Mar. 2025.

Kids Definition

interstitial

adjective
in·​ter·​sti·​tial ˌint-ər-ˈstish-əl How to pronounce interstitial (audio)
: relating to or located in the interstices
interstitially adverb

Medical Definition

interstitial

adjective
in·​ter·​sti·​tial ˌint-ər-ˈstish-əl How to pronounce interstitial (audio)
1
: situated within but not restricted to or characteristic of a particular organ or tissue
used especially of fibrous tissue
2
: affecting the interstitial tissues of an organ or part
interstitial hepatitis
3
: occurring in the part of a fallopian tube in the wall of the uterus
interstitial pregnancy
interstitially adverb
Last Updated: - Updated example sentences
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