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lipophilic
adjective
li·po·phil·ic
ˌlī-pə-ˈfi-lik
ˌli-
: having an affinity for lipids (such as fats)
a lipophilic metabolite
Examples of lipophilic in a Sentence
Recent Examples on the Web
Loaded into micelles, aggregates of molecules that are both water-loving (hydrophilic) and fat-loving (lipophilic), that are delivered intranasally means the treatment quickly arrives in the brain via the nose-to-brain anatomical pathway, bypassing the BBB completely.
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New Atlas, 23 July 2024
Researchers at the Mitchell Center for Neurodegenerative Diseases, University of Texas, tested a spray containing tiny lipophilic micelles (oil/fat particles that can carry substances through water) on aging mice, administering the treatment through their noses.
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Shannon McDonagh, Newsweek, 10 July 2024
Yadav said that vitamins could be administered transdermally, but only if they were formulated as nanoparticles and encased in a lipophilic (fat-soluble) substance.
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Rachel Murphy, Verywell Health, 11 June 2024
Hydrophilic molecules love water, while lipophilic molecules love fat.
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Caroline Delbert, Popular Mechanics, 6 May 2023
How Whiskey Aromas Evolve: Neat → Diluted Smoky → Pome fruit Vanilla + Oak → Corn + Grains Oak → Cedar Overall, the dilution of hydrophobic (water-hating) or lipophilic (fat-loving) molecules explains a lot of why the aromas changed so noticeably.
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Caroline Delbert, Popular Mechanics, 6 May 2023
The ingredient is a beta-hydroxy acid, and one that’s lipophilic.
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Melanie Rud, Peoplemag, 7 Apr. 2023
Instead, this gentle cleanser uses lipophilic esters and squalane to clean skin in the least irritating way.
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Grooming Playbook, The Salt Lake Tribune, 24 May 2022
Instead, the Squalane Cleanser uses a blend of hydrating lipophilic esters to remove surface dirt and excess oil more gently.
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The Salt Lake Tribune, 9 May 2022
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Word History
First Known Use
1939, in the meaning defined above
Dictionary Entries Near lipophilic
Cite this Entry
“Lipophilic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lipophilic. Accessed 22 Feb. 2025.
Medical Definition
lipophilic
adjective
li·po·phil·ic
ˌlip-ə-ˈfil-ik
ˌlīp-
: having an affinity for lipids (as fats)
a lipophilic metabolite
compare hydrophilic, lyophilic, oleophilic
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