manic-depressive illness

noun

: bipolar disorder

Examples of manic-depressive illness in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Bipolar disorder, also known as manic-depressive illness, is characterized by episodic fluctuations in mood, concentration or energy levels. — Anna Funk, Discover Magazine, 22 May 2019 Bipolar disorder is a manic-depressive illness of the brain that causes extreme changes in mood and energy levels, according to the National Institute of Mental Health. — Vanessa Etienne, Peoplemag, 21 Sep. 2022

Word History

First Known Use

1951, in the meaning defined above

Time Traveler
The first known use of manic-depressive illness was in 1951

Rhymes for manic-depressive illness

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manic-depressive illness
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Cite this Entry

“Manic-depressive illness.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/manic-depressive%20illness. Accessed 30 Mar. 2025.

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Medical Definition

manic-depressive illness

noun
: bipolar disorder

More from Merriam-Webster on manic-depressive illness

Britannica.com: Encyclopedia article about manic-depressive illness

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