microbiome

noun

mi·​cro·​bi·​ome ˌmī-krō-ˈbī-ˌōm How to pronounce microbiome (audio)
1
: a community of microorganisms (such as bacteria, fungi, and viruses) that inhabit a particular environment and especially the collection of microorganisms living in or on the human body
Your body is home to about 100 trillion bacteria and other microbes, collectively known as your microbiome.Carl Zimmer
… what's arguably become the hottest area of medicine: microbiome research, an emerging field that's investigating how the bacteria that live in and on our bodies affect our health.Sunny Sea Gold
2
: the collective genomes of microorganisms inhabiting a particular environment and especially the human body
They form one community among the many that make up the human microbiome: the full genetic complement of bacteria and other organisms at home on your skin, gums, and teeth, in your genital tract, and especially in your gut.Nathan Wolfe

Examples of microbiome in a Sentence

Recent Examples on the Web
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Nadeau, who was not involved in the new study, notes that astronauts often have trouble staying healthy in space, not only because of the effects of microgravity but also because of changes in their gut microbiome. Gayoung Lee, Scientific American, 7 Apr. 2025 Damage To Gut Health Our gut microbiome — the diverse community of bacteria in our digestive system — plays a crucial role in immunity, digestion and mental health. Ximena Araya-Fischel, Forbes, 25 Mar. 2025 Other oncologists are investigating their own ways to improve responses to cancer treatment through the gut microbiome. David Cox, NBC News, 14 Mar. 2025 While more research can help clarify the link between the gut microbiome and multiple sclerosis, these findings offer a promising new direction for understanding and treating this disease. Ashutosh Mangalam, The Conversation, 3 Mar. 2025 See All Example Sentences for microbiome

Word History

Etymology

micro- + biome

First Known Use

1952, in the meaning defined at sense 1

Time Traveler
The first known use of microbiome was in 1952

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Cite this Entry

“Microbiome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/microbiome. Accessed 16 Apr. 2025.

Medical Definition

microbiome

noun
mi·​cro·​bi·​ome ˌmī-krō-ˈbī-ˌōm How to pronounce microbiome (audio)
1
: a community of microorganisms (such as bacteria, fungi, and viruses) that inhabit a particular environment and especially the collection of microorganisms living in or on the human body
The intestinal microbiome consists of the microorganisms that inhabit the gut.Clara Abraham et al., The New England Journal of Medicine
Collectively known as the microbiome, this community may play a role in regulating one's risk of obesity, asthma and allergies.Carrie Arnold, Scientific American
The human oral microbiome comprises all microbial species in the oral cavity.Naomi P. O'Grady, The Journal of the American Medical Association
2
: the collective genomes of microorganisms inhabiting a particular environment and especially the human body
As part of a new citizen-science initiative called the American Gut project, the lab sequenced my microbiome—that is, the genes not of "me," exactly, but of the several hundred microbial species with whom I share this body.Michael Pollan, The New York Times
Together, the genomes of these microbial symbionts (collectively defined as the microbiome) provide traits that humans did not need to evolve on their own.Peter J. Turnbaugh et al., Nature
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