: having or involving a single neural synapse

Word History

First Known Use

1942, in the meaning defined above

Time Traveler
The first known use of monosynaptic was in 1942

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Cite this Entry

“Monosynaptic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/monosynaptic. Accessed 28 Mar. 2025.

Medical Definition

monosynaptic

adjective
: having or involving a single neural synapse
monosynaptically adverb
monosynaptically activated neurons
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