naloxone

noun

nal·​ox·​one na-ˈläk-ˌsōn How to pronounce naloxone (audio)
: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
That same year, Elgin had 11 locations where naloxone was distributed, according to that same online dashboard. Ismael M. Belkoura, Chicago Tribune, 7 Mar. 2025 National research suggests these distribution efforts, often spearheaded by local harm-reduction organizations, have led to quicker administration of naloxone. Ben Cocchiaro, The Conversation, 11 Feb. 2025 The promising news comes as the overdose antidote naloxone becomes more widely available. Taylor Wilson, USA TODAY, 24 Jan. 2025 Kansans can request free naloxone by visiting bit.ly/kansasnaloxone, and Missourians can request free naloxone by visiting bit.ly/missourinaloxone. Individuals across the KC metro can also get free naloxone from the following locations during open hours. Natalie Wallington, Kansas City Star, 16 Jan. 2025 See All Example Sentences for naloxone

Word History

Etymology

N-allyl + hydroxy- + -one

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of naloxone was in 1964

Browse Nearby Words

Cite this Entry

“Naloxone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/naloxone. Accessed 23 Mar. 2025.

Medical Definition

naloxone

noun
: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!