: relating to or being any of the eukaryotic proteins (such as DNA polymerase) that form complexes with DNA but are not considered histones

Word History

First Known Use

circa 1966, in the meaning defined above

Time Traveler
The first known use of nonhistone was circa 1966

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Cite this Entry

“Nonhistone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nonhistone. Accessed 25 Mar. 2025.

Medical Definition

nonhistone

adjective
: relating to or being any of the eukaryotic proteins (as DNA polymerase) that form complexes with DNA but are not considered histones
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