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In both men and women, these hormones help to increase the activity of osteoblasts.—Caroline C. Boyle, USA TODAY, 22 Mar. 2025 In particular, a joint study by Creighton University in Nebraska and the University of Miami, Florida, found that caffeine reduced the expression of vitamin D receptors on osteoblasts—the cells in our bodies responsible for producing bone.—Fiona Embleton, Glamour, 18 Mar. 2025 Bone formation is coupled with bone resorption, as osteoblasts build bone at the same rate that osteoclasts resorb bone.—Lorena Meouchi, Vogue, 6 Mar. 2025 The disease occurs when there's an imbalance between a person's osteoblasts – which are bone-building cells – and their osteoclasts, which are bone-degrading cells.—Ben Coxworth, New Atlas, 2 Feb. 2025 Throughout life, our bone tissue is maintained by bone-building osteoblasts working in harmony with counterpart cells called osteoclasts, which break down old bone that needs replacing.—Jolene Edgar, Allure, 11 Feb. 2025 Manganese is also involved in skeletal health by regulating the activity of osteoblasts and osteoclasts, specialized cells that build up and break down bone tissue, respectively.6
Manganese is also required to produce collagen, a major component of bone tissue and your skin.—Jillian Kubala, Health, 5 Feb. 2025 When those cells outnumber the osteoblasts, though, there's an overall loss of bone tissue, resulting in weaker, more fragile bones.—Ben Coxworth, New Atlas, 2 Feb. 2025 In modern skeletons, tiny blood vessels that burrow into the bone’s hard matrix provide an inroad for cells called osteoclasts to eat away old bone and for cells called osteoblasts to begin making new bone.—Byelizabeth Pennisi, science.org, 10 Jan. 2025
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