prophylaxis

noun

pro·​phy·​lax·​is ˌprō-fə-ˈlak-səs How to pronounce prophylaxis (audio)
 also  ˌprä-
plural prophylaxes ˌprō-fə-ˈlak-ˌsēz How to pronounce prophylaxis (audio)
 also  ˌprä-
: measures designed to preserve health (as of an individual or of society) and prevent the spread of disease

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In Greek, phylax means "guard", so prophylactic measures guard against disease by taking action ahead of time. Thus, for example, before the polio vaccine became available, prophylaxis against polio included avoiding crowds and public swimming pools. These days a well-known kind of prophylactic is used to prevent sexually transmitted diseases; but prophylactic measures only work when people use them.

Examples of prophylaxis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These results support continued use of oseltamivir as the first-line treatment and for post-exposure prophylaxis in close contacts of infected individuals. John Drake, Forbes.com, 27 Mar. 2025 But as antiretroviral exposure, ART during pregnancy, and pre-exposure prophylaxis (PrEP) reshaped the landscape, the Elton John AIDS Foundation demonstrated agility and shifted its focus to prevention and systemic change. Jeetendr Sehdev, Forbes, 26 Feb. 2025 People who are exposed to HIV have only 72 hours—less than the amount of time many clinics have now been closed—to begin a medication regimen called post-exposure prophylaxis that can help prevent infection. Hana Kiros, The Atlantic, 5 Feb. 2025 Even though deaths are rare – fewer than 10 people a year die from rabies in the US – about 60,000 people receive post-exposure prophylaxis after rabies exposure each year. Carma Hassan, CNN, 3 Dec. 2024 See All Example Sentences for prophylaxis

Word History

Etymology

borrowed from New Latin, from Greek prophylak-, stem of prophylássein "to keep guard before a place, be on guard, (middle voice) to be on one's guard against, take precautions against" (from pro- pro- entry 1 + phylássein "to keep watch on, guard, preserve," derivative of phylak-, phýlax "guard, guardian, protector") + -sis -sis — more at phylactery

First Known Use

1683, in the meaning defined above

Time Traveler
The first known use of prophylaxis was in 1683

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Cite this Entry

“Prophylaxis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prophylaxis. Accessed 12 Apr. 2025.

Medical Definition

prophylaxis

noun
pro·​phy·​lax·​is -ˈlak-səs How to pronounce prophylaxis (audio)
plural prophylaxes -ˈlak-ˌsēz How to pronounce prophylaxis (audio)
: measures designed to preserve health and prevent the spread of disease : protective or preventive treatment
prophylaxis against viral diseases
a paste containing fluorine for dental prophylaxis

More from Merriam-Webster on prophylaxis

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