sepsis

noun

sep·​sis ˈsep-səs How to pronounce sepsis (audio)
plural sepses ˈsep-ˌsēz How to pronounce sepsis (audio)
: a potentially life-threatening, systemic response of the immune system that results from the spread of pathogenic agents (such as bacteria or viruses) and their toxins to the bloodstream from a localized infection (as of the lungs), that involves both inflammatory and immunosuppressive activity, that is marked especially by fever, chills, rapid heart rate and breathing, fatigue, confusion, increased blood coagulation, hypotension, impaired microcirculation, and organ dysfunction, and that may progress to septic shock

Note: The primary cause of sepsis is pneumonia with secondary causes commonly including infections of the abdominal cavity and urinary tract.

compare septicemia

Examples of sepsis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In 2021, he was hospitalized for six days in California due to a sepsis infection that had spread to his bloodstream. Josh Hammer, Newsweek, 24 Dec. 2024 Infection in the heart and bloodstream: An endocarditis infection can also lead to sepsis. Angela Ryan Lee, Health, 28 Dec. 2024 Immediate medical attention is crucial, as the infection can lead to organ failure, sepsis, shock, and even death. David Faris, Newsweek, 27 Dec. 2024 Like her mother's infection, it had not been treated quickly and had progressed to sepsis. Cara Lynn Shultz, People.com, 3 Dec. 2024 See all Example Sentences for sepsis 

Word History

Etymology

New Latin, from Greek sēpsis decay, from sēpein to putrefy

First Known Use

1863, in the meaning defined above

Time Traveler
The first known use of sepsis was in 1863

Dictionary Entries Near sepsis

Cite this Entry

“Sepsis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sepsis. Accessed 18 Jan. 2025.

Medical Definition

sepsis

noun
sep·​sis ˈsep-səs How to pronounce sepsis (audio)
plural sepses ˈsep-ˌsēz How to pronounce sepsis (audio)
: a potentially life-threatening, systemic response of the immune system that results from the spread of pathogenic agents (as bacteria or viruses) and their toxins to the bloodstream from a localized infection (as of the lungs), that involves both inflammatory and immunosuppressive activity, and that is marked especially by fever, chills, rapid heart rate and breathing, fatigue, confusion, increased blood coagulation, hypotension, impaired microcirculation, and organ dysfunction, and that may progress to septic shock

Note: The primary cause of sepsis is pneumonia with secondary causes commonly including infections of the abdominal cavity and urinary tract.

compare multiple organ dysfunction syndrome, septicemia

More from Merriam-Webster on sepsis

Last Updated: - Updated example sentences
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