sepsis

noun

sep·​sis ˈsep-səs How to pronounce sepsis (audio)
plural sepses ˈsep-ˌsēz How to pronounce sepsis (audio)
: a potentially life-threatening, systemic response of the immune system that results from the spread of pathogenic agents (such as bacteria or viruses) and their toxins to the bloodstream from a localized infection (as of the lungs), that involves both inflammatory and immunosuppressive activity, that is marked especially by fever, chills, rapid heart rate and breathing, fatigue, confusion, increased blood coagulation, hypotension, impaired microcirculation, and organ dysfunction, and that may progress to septic shock

Note: The primary cause of sepsis is pneumonia with secondary causes commonly including infections of the abdominal cavity and urinary tract.

compare septicemia

Examples of sepsis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The months that followed were filled with more hospitalizations, transfusions, and a serious bout of sepsis. John W. Dean, MSNBC Newsweek, 7 Apr. 2025 Trebor died of sepsis on March 11 at the Los Angeles Medical Center, his wife, Deirdre Hennings, told The Hollywood Reporter. Brenton Blanchet, People.com, 5 Apr. 2025 Trebor died March 11 at Los Angeles Medical Center of sepsis, his wife, Deirdre Hennings, told The Hollywood Reporter. Mike Barnes, HollywoodReporter, 4 Apr. 2025 But if it’s not removed within hours or days, the woman could be at risk of sepsis, or of losing her uterus. Sarah Cutler, Idaho Statesman, 2 Apr. 2025 See All Example Sentences for sepsis

Word History

Etymology

New Latin, from Greek sēpsis decay, from sēpein to putrefy

First Known Use

1863, in the meaning defined above

Time Traveler
The first known use of sepsis was in 1863

Browse Nearby Words

Cite this Entry

“Sepsis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sepsis. Accessed 13 Apr. 2025.

Medical Definition

sepsis

noun
sep·​sis ˈsep-səs How to pronounce sepsis (audio)
plural sepses ˈsep-ˌsēz How to pronounce sepsis (audio)
: a potentially life-threatening, systemic response of the immune system that results from the spread of pathogenic agents (as bacteria or viruses) and their toxins to the bloodstream from a localized infection (as of the lungs), that involves both inflammatory and immunosuppressive activity, and that is marked especially by fever, chills, rapid heart rate and breathing, fatigue, confusion, increased blood coagulation, hypotension, impaired microcirculation, and organ dysfunction, and that may progress to septic shock

Note: The primary cause of sepsis is pneumonia with secondary causes commonly including infections of the abdominal cavity and urinary tract.

compare multiple organ dysfunction syndrome, septicemia
Last Updated: - Updated example sentences
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