side effect

noun

: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Some say that smaller doses can reduce side effects—such as nausea, diarrhea, and vomiting—while maintaining their weight loss at a lower cost. Fran Kritz, Verywell Health, 21 Mar. 2025 Higher estrogen levels also correlate with more severe side effects, pointing to the role of hormonal cycles in drug response. Alex Knapp, Forbes, 19 Mar. 2025 Just one patient out of 21 in Vitanza’s trial had a severe side effect, bleeding in the tumor. Kaitlin Sullivan, NBC News, 19 Mar. 2025 The supplement can lead to side effects like nausea, dizziness, headaches, rashes, nightmares, and gastritis. Angela Haupt, TIME, 18 Mar. 2025 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 29 Mar. 2025.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
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