1
: not opposed
an unopposed invasion
: having no opponent
a politician who is running for election unopposed
2
medical : being or relating to estrogen replacement therapy in which a progestin (such as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (such as endometrial cancer) associated with estrogen used alone
A woman who has had her uterus removed can take the estrogen "unopposed"—that is, without the addition of progestin. Consumer Reports

Examples of unopposed in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Jeff Sessions went from running unopposed in a 2014 general election for Senate in Alabama to failing to break 40% of the vote in a Republican primary runoff six years later following his break with Trump. W. James Antle Iii, Washington Examiner - Political News and Conservative Analysis About Congress, the President, and the Federal Government, 12 Mar. 2025 In West Lakeland Township, Chairman Phillip Moosbrugger ran unopposed and received 136 votes. Mary Divine, Twin Cities, 12 Mar. 2025 He was reelected last November after running unopposed. Riley Beggin, USA TODAY, 5 Mar. 2025 The fact that Repay ran unopposed speaks volumes of the confidence the party has in him, Wieser said. Alexandra Kukulka, Chicago Tribune, 3 Mar. 2025 See All Example Sentences for unopposed

Word History

First Known Use

1625, in the meaning defined at sense 1

Time Traveler
The first known use of unopposed was in 1625

Browse Nearby Words

Cite this Entry

“Unopposed.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/unopposed. Accessed 24 Mar. 2025.

Medical Definition

unopposed

adjective
: being or relating to estrogen replacement therapy in which a progestin (as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (as endometrial cancer) associated with estrogen used alone
Last Updated: - Updated example sentences
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