: an abnormal red blood cell having several unevenly spaced and variously shaped cytoplasmic projections with blunt tips
The presence of acanthocytes implies advanced liver disease and carries a worse prognosis. Bruce R. Bacon et al., Comprehensive Clinical Hepatology

called also spur cell

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“Acanthocyte.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/acanthocyte. Accessed 22 Mar. 2025.

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