How to Use substance in a Sentence

substance

noun
  • The results of the study give substance to their theory.
  • The floor was covered with a white, powdery substance that turned out to be flour.
  • He had a history of substance abuse.
  • When has he ever said anything of substance?
  • The pancreas secretes a substance called insulin.
  • That’s not to say the yacht is all style and no substance, though.
    Rachel Cormack, Robb Report, 17 Apr. 2023
  • The judge found the substance caused Ethan Bherwani’s death.
    Brian Hallenbeck, Hartford Courant, 28 July 2024
  • The study found that there were declines across substances.
    Gord Magill, Newsweek, 21 Dec. 2024
  • Even some insects and birds seem to dislike the substance.
    Sarah Keartes, Smithsonian Magazine, 23 Nov. 2022
  • But as with any mind-altering substance, there are rules of the road.
    Audrey Williams, Essence, 18 Nov. 2022
  • The conscious substance, that type of hip-hop is seldom heard now.
    Andre Gee, Rolling Stone, 26 July 2024
  • Katharine Murphy, a substance abuse counselor with St. Joseph, stopped him at the door.
    Los Angeles Times, 11 Jan. 2023
  • Look, the substance of the attack has some real problems, right?
    ABC News, 30 July 2023
  • Images taken of the substance showed something red spread along the road.
    Jade Jackson, The Indianapolis Star, 9 Aug. 2024
  • Thomas will be treated in prison for substance abuse and mental health.
    Ike Morgan | Imorgan@al.com, al, 19 Sep. 2023
  • Since the advent of television, style has played a far more important role than substance in the armies of the right and the left.
    Joe Klein, Washington Post, 12 Jan. 2023
  • The gathering proved to be a meta affair, more about process than substance.
    Paul Elie, The New Yorker, 8 Nov. 2023
  • And if there are any more problems because of her substance abuse, all bets will be off.
    Jeanne Phillips, The Mercury News, 10 Nov. 2024
  • Antigens are a substance on red blood cells like a protein.
    Caitlin McLean, USA TODAY, 21 Sep. 2022
  • When asked about substance abuse, girls had often ranked better or around the same compared to boys over the past decade.
    Alexander Tin, CBS News, 13 Feb. 2023
  • But there’s much more to this exuberant movie, in substance and in style.
    Richard Brody, The New Yorker, 10 Oct. 2022
  • Gingrich has been working with McCarthy and his team to craft the style and substance of the proposal.
    CBS News, 23 Sep. 2022
  • Your body and food have a substance called uric acid that usually dissolves in the bloodstream.
    Anne Harding, Health, 25 Aug. 2023
  • While most substance use decreased over time among all groups, cannabis and vape use increased.
    Saleen Martin, USA TODAY, 29 Sep. 2022
  • Waste paper and plastic were found in the packages and there were no substances hazardous to safety, the JCS said.
    Yoonjung Seo, CNN, 9 June 2024
  • That the substance was applied to the inside means that, as the mounts age, arsenic is exposed around the seams, where the skin separates from the mannequin.
    Katrina Miller, New York Times, 23 Sep. 2023
  • They are trained to help in a mental health, suicide or substance use crisis.
    Jennifer Brookland, Detroit Free Press, 7 Oct. 2022
  • We were raised by single moms who had substance abuse issues.
    Victoria Uwumarogie, Essence, 18 Oct. 2023
  • For the full mice, however, even just the sight of the sugary substance caused the neurons to activate and flood their system with endorphins.
    Stephanie Edwards, Discover Magazine, 13 Feb. 2025
  • Oils may reduce hair damage by preventing harmful substances from entering the hair follicle.
    Amy Brownstein, Ms, Rdn, Verywell Health, 31 Jan. 2025

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'substance.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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