leptin

noun

lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

Examples of leptin in a Sentence

Recent Examples on the Web
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Ghrelin, an appetite stimulant, rises when you are sleep-deprived, and leptin decreases. Judy Stone, Forbes, 10 Mar. 2025 Lack of sleep is known to increase hunger hormones (like ghrelin) and decrease satiety hormones, like leptin, which can cause users to overeat, undermining how GLP-1s suppress appetite. Lauryn Higgins, Flow Space, 6 Mar. 2025 At the same time levels of a hormone called leptin that tells the brain when the stomach is full plummet. Sandee Lamotte, CNN, 23 Jan. 2025 This article covers leptin, what contributes to leptin resistance, and leptin's role in obesity. Kelly Burch, Verywell Health, 3 Dec. 2024 See All Example Sentences for leptin

Word History

Etymology

Greek leptos slender + English -in entry 1

First Known Use

1995, in the meaning defined above

Time Traveler
The first known use of leptin was in 1995

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Cite this Entry

“Leptin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leptin. Accessed 24 Mar. 2025.

Medical Definition

leptin

noun
lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

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