How to Use leptin in a Sentence

leptin

noun
Definition of leptinnext
  • The more fat on a person’s body, the more leptin is released.
    — Gina Kolata, New York Times, 22 July 2016
  • At the same time, leptin, the hormone that signals fullness, may plunge.
    — Samantha Lauriello, Health, 26 June 2023
  • Amgen bought the rights to leptin and, in 1996, began testing it in people.
    — Gina Kolata, New York Times, 17 Aug. 2023
  • Higher levels of leptin in your bloodstream mean more fat on your body.
    — Jessica Migala, NBC News, 19 Sep. 2017
  • So why did a drug to provide people with leptin never make it to market?
    — Judith Newman, New York Times, 28 Dec. 2016
  • So, their bodies were not relying solely on leptin to track and respond to weight changes.
    — Gretchen Reynolds, New York Times, 17 Jan. 2018
  • The researchers next repeated the procedure, but in mice that had been bred to produce very little leptin.
    — Gretchen Reynolds, New York Times, 17 Jan. 2018
  • One of those cytokines is leptin, a satiety hormone secreted by fat tissue, which women tend to have more of than men.
    — Amanda MacMillan, Health.com, 1 Aug. 2017
  • Running low on rest can affect ghrelin and leptin, the hunger and satiety hormones.8 Too much ghrelin makes your body crave fatty and sugary foods, said Dr. Winter.
    — Rachel Swalin, Health, 6 Aug. 2023
  • That's partly due to the connection between sleep and the peptides that regulate your appetite: ghrelin and leptin.
    — Sandee Lamotte, CNN, 19 July 2017
  • In the longer term, the hypothalamus takes cues from an appetite-suppressant called leptin.
    — Cody Cottier, Discover Magazine, 8 Dec. 2023
  • Not getting enough shut-eye also throws hunger and metabolism hormones like leptin and ghrelin out of whack.
    — Melissa Matthews, Men's Health, 10 Aug. 2023
  • Their levels of the hormone leptin, which is responsible for feeling full, dropped, and the levels of the appetite- inducing hormone ghrelin went up.
    — Alexandra Sifferlin, Time, 1 May 2017
  • The contestants started out with normal levels of leptin.
    — Gina Kolata, New York Times, 2 May 2016
  • And mice with lots of leptin in their bloodstreams lost weight when given Celastrol, but the compound had no effect on mice with no leptin, or in mice without any leptin receptors.
    — K. N. Smith, Discover Magazine, 21 May 2015
  • Other gene variants — like mutations in FTO or the gene for leptin, an energy-balancing hormone — had been linked to overeating or fat cell type.
    — Sylvia Tara, Discover Magazine, 6 Feb. 2017
  • African Mango Extract helps to increase leptin levels, which can lead to a decrease in appetite and an increase in metabolism.
    — Discover Magazine, 29 Apr. 2023
  • He was spurred to leave medicine and learn about drug development by the discovery in the mid-1990s of leptin, a hormone that suppresses appetite and appeared to be a promising obesity treatment.
    — Megan Molteni and Elaine Chen, STAT, 30 Sep. 2023
  • As a result, leptin gets unblocked—sometimes in as little as a week, resulting in an end to ‘insatiable hunger’ and compulsive grazing.
    — Stephanie Walden, USA TODAY, 11 Jan. 2018
  • Binge eating and restrictive diets could be causes for your leptin levels to be unbalanced.
    — Melanie Laughman, The Enquirer, 27 May 2023
  • Want to increase your leptin levels, suppress your appetite, and supercharge your metabolism around the clock?
    — Amber Smith, Discover Magazine, 3 Apr. 2024
  • Also involved in the complex process are hormones, particularly the two that are often referred to as hunger hormones, leptin and ghrelin.
    — Amanda Gardner, PEOPLE.com, 19 Dec. 2017
  • Some years ago, scientists did discover one of the likely mechanisms, which involves leptin, a hormone released by fat cells.
    — Gretchen Reynolds, New York Times, 17 Jan. 2018
  • But that doesn’t work for people who have developed resistance to leptin, a hormone that suppresses appetite.
    — Karen Kaplan, Los Angeles Times, 15 Apr. 2024
  • The diet increased the levels of leptin—a hormone produced by fat cells that usually signals satiety in the brain—in the bone marrow, which promoted the development of fat cells instead of bone cells.
    — Emma Yasinski, Science | AAAS, 5 Sep. 2017
  • This condition, known as leptin resistance, often plays a role in overeating and obesity.
    — Cody Cottier, Discover Magazine, 8 Dec. 2023
  • Also implicated is the hormone leptin, which is released by fat cells and is responsible for feelings of satiety.
    — Jeffrey Kluger, Time, 6 Nov. 2019
  • While this was exciting, more research did not support leptin as a big contributor to obesity.
    — Bryant Stamford, The Courier-Journal, 22 Mar. 2018
  • Hormonal signals also act on the brain: leptin, a hormone produced by fat cells, sends signals to the hypothalamus to inhibit hunger.
    — Andrew Chapman, Longreads, 18 Apr. 2024
  • Consistently logging eight hours of sleep a night can help boost low testosterone levels and have a positive impact on cortisol, leptin and insulin levels.
    — Christy Brissette, Washington Post, 5 Aug. 2019

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'leptin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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