1
as in rebellious
given to resisting authority or another's control
refractory players will be ejected from the game
Synonyms & Similar Words
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Antonyms & Near Antonyms
2
as in stubborn
given to resisting control or discipline by others
believing that rules are only for other people, he's been refractory virtually his entire life
Synonyms & Similar Words
Antonyms & Near Antonyms
Example Sentences
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Recent Examples of refractory
This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA.
—
Kansas City Star, 13 May 2024
Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study.
—Meghana Keshavan, STAT, 15 Apr. 2024
All of the children had rare, relapsed or refractory cancers and were running out of treatment options.
—Michelle Marchante, Miami Herald, 11 Apr. 2024
Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients.
—Damian Garde, STAT, 13 Dec. 2023
See All Example Sentences for refractory
Kansas City Star, 13 May 2024
Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study.
—Meghana Keshavan, STAT, 15 Apr. 2024
All of the children had rare, relapsed or refractory cancers and were running out of treatment options.
—Michelle Marchante, Miami Herald, 11 Apr. 2024
Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients.
—Damian Garde, STAT, 13 Dec. 2023
See All Example Sentences for refractory
Recent Examples of Synonyms for refractory
Adjective
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And if his readership remained informed on his doings, the prince and his supporters didn’t succeed in silencing him and the rest of the rebellious faction.—
Emily Zarevich,
JSTOR Daily,
4 Apr. 2025
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Wearing cowboy boots with shorts is not only a bold stylistic choice but also a practical way to dress for warm weather without giving up the rustic and rebellious touch that the boots bring.—
René Chávez Esparza,
Glamour,
31 Mar. 2025
Adjective
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Described by family as larger-than-life in personality and stature, the 6-foot-5-inch Wesley is remembered as a jovial, fiercely stubborn man with a quick wit and passion for advocacy.—
Silas Morgan,
The Orlando Sentinel,
29 Mar. 2025
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Happy Birthday for Saturday, March 29, 2025: You are opinionated and stubborn.—
Georgia Nicols,
Denver Post,
29 Mar. 2025
Adjective
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President Trump’s military and intelligence leaders inadvertently shared classified military information on a Houthi rebel attack with a magazine editor which was published online.—
Rick Pozniak,
Boston Herald,
1 Apr. 2025
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In the fresh extended footage shown, DiCaprio’s former yippie Bob is seen negotiating with a difficult underground rebel contact who knows the whereabouts of his daughter (played by Chase Infiniti).—
Nancy Tartaglione,
Deadline,
1 Apr. 2025
Adjective
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For recalcitrant teams, Scherzer would also remove the runner who automatically starts each inning after the ninth in scoring position on second base, creating a significant handicap.—
Bruce Schoenfeld Robert Fass Tanya Pérez Brian St. Pierre,
New York Times,
26 Mar. 2025
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Milla — a young woman who feels disillusioned by doctors that treat her like a recalcitrant child, directing even conversations about her treatment to her father instead of her — finds false security in quacks selling enemas and juice cleanses.—
Angie Han,
The Hollywood Reporter,
5 Feb. 2025
Adjective
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Related article Palestinian and Israeli filmmakers make defiant speech after winning best documentary Oscar For Ballal, the assault – and Netanyahu’s moves – are even more of a reason to continue to fight for his community.—
Kareem Khadder,
CNN Money,
27 Mar. 2025
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Two months into his term, President Trump is growing more defiant, creative and ruthless in his pursuit of a central campaign promise: exacting revenge on his political enemies.—
Zachary Basu,
Axios,
21 Mar. 2025
Adjective
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Infrastructure poses an equally intractable challenge.—
Priya Oberoi,
Forbes.com,
27 Mar. 2025
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The most intractable puzzle, for John, is how to act like a socially confident family man unfazed by the outside world.—
Sarah Larson,
The New Yorker,
21 Mar. 2025
Adjective
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Common Mental Health Conditions in Men Depression Depression causes disruptive, uncontrollable feelings of sadness and emptiness.—
Mark Gurarie,
Verywell Health,
3 Apr. 2025
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Slippery Slope Thinking Fuels A Fear Of Change People with strong slippery slope beliefs tend to assume that one small change will lead to inevitable, uncontrollable negative consequences.—
Mark Travers,
Forbes.com,
26 Mar. 2025
Adjective
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The federal government, with its millions of employees, has ballooned into an unmanageable monstrosity, consuming trillions of taxpayer dollars while failing at even the most basic functions.—
Paul Du Quenoy,
MSNBC Newsweek,
26 Mar. 2025
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When the herd grew unmanageable, Mexican-Spanish vaqueros (cowboys) were brought in from California to teach locals how to rope and herd cattle.—
Sophie-Claire Hoeller,
Vogue,
21 Mar. 2025
Cite this Entry
“Refractory.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractory. Accessed 13 Apr. 2025.
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